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1

Mitogenic and polyclonal B cell activation activities of synthetic lipid A analogues

Yoshio Kumazawa, Motohiro Matsuura, Yoko Nakatsuru-Watanabe, Mitsuru Fukumoto, Chiaki Nishimura, J. Yuzuru Homma, Masaru Inage, Shoichi Kusumoto, Tetsuo Shiba

Journal:

European Journal of Immunology

Année:

1984

Langue:

english

Fichier:

PDF, 552 KB

english, 1984

2

B cell activation and adjuvant activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A

Yoshio Kumazawa, Motohiro Matsuura, J. Yuzuru Homma, Yoko Nakatsuru, Makoto Kiso, Akira Hasegawa

Journal:

European Journal of Immunology

Année:

1985

Langue:

english

Fichier:

PDF, 325 KB

english, 1985

3

Structural requirements for inducing in vitro B lymphocyte activation by chemically synthesized derivatives related to the nonreducing D-glucosamine subunit of lipid A

Yoshio Kumazawa, Motohiro Matsuura, Tokuei Maniyama, J. Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

European Journal of Immunology

Année:

1986

Langue:

english

Fichier:

PDF, 558 KB

english, 1986

4

Effect of stereospecificity of chemically synthesized lipid A-subunit analogues GLA-27 and GLA-40 on the expression of immunopharmacological activities

Yoshio Kumazawa, Satoru Ikeda, Hiroaki Takimoto, Chiaki Nishimura, Mitsunobu Nakatsuka, J. Yuzuru Homma, Akihiro Yamamoto, Makoto Kiso, Akira Hasegawa

Journal:

European Journal of Immunology

Année:

1987

Langue:

english

Fichier:

PDF, 556 KB

english, 1987

5

The protein moiety of the endotoxin of Pseudomonas aeruginosa

J. Yuzuru Homma

Journal:

Journal of Basic Microbiology

Année:

1968

Langue:

english

Fichier:

PDF, 1.59 MB

english, 1968

6

Immunopharmacological activities of chemically synthesized lipid a-subunit analogue GLA-27 combined with muramyl dipeptide via spacers of different carbon chain length

Ikeda Satoru, Yoshio Kumazawa, Kazutoshi Sai, Chiaki Nishimura, Mitsunobu Nakatsuka, Homma^ J. Yuzuru, Akihiro Yamamoto, Makoto Kiso, Akira Hasegawa

Journal:

International Journal of Immunopharmacology

Année:

1988

Langue:

english

Fichier:

PDF, 574 KB

english, 1988

7

Enhancement of nonspecific resistance to bacterial infections and tumor regressions by treatment with synthetic lipid A-subunit analogs. Critical role of N- and 3-O-linked acyl groups in 4-O-phosphono-D-glucosamine derivatives

Mitsunobu Nakatsuka, Yoshio Kumazawa, Motohiro Matsuura, J. Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

International Journal of Immunopharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 674 KB

english, 1989

8

Enhancement of nonspecific resistance to microbial infections of synthetic lipid a-subunit analogues of GLA-27 modified at the C1 position of the glucosamine backbone

Mitsunobu Nakatsuka, Satoru Ikeda, Yoshio Kumazawa, Motohiro Matsuura, Chiaki Nishimura, J. Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

International Journal of Immunopharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 410 KB

english, 1990

9

Inhibition in mice of experimental metastasis of B16 melanoma by the synthetic lipid A-subunit analogue GLA-60

Mitsunobu Nakatsuka, Yoshio Kumazawa, J. Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

International Journal of Immunopharmacology

Année:

1991

Langue:

english

Fichier:

PDF, 605 KB

english, 1991

10

Pargamicin A, a Novel Cyclic Peptide Antibiotic from Amycolatopsis sp.

Igarashi, Masayuki, Sawa, Ryuichi, Kinoshita, Naoko, Hashizume, Hideki, Nakagawa, Naoko, Homma, Yoshiko, Nishimura, Yoshio, Akamatsu, Yuzuru

Journal:

The Journal of Antibiotics

Année:

2008

Langue:

english

Fichier:

PDF, 379 KB

english, 2008

11

Phosphodiesterase type 4 inhibition of activated polymorphonuclear leukocytes in a simulated extracorporeal circulation model

Yukio Sato, Yuji Hiramatsu, Satoshi Homma, Shyoko Sato, Masataka Onizuka, Yuzuru Sakakibara

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Année:

2003

Langue:

english

Fichier:

PDF, 143 KB

english, 2003

12

Regions of the Lipopolysaccharide of Pseudomonas aeruginosa Essential for Antitumor and Interferon-Inducing Activities

Ken-ichi TANAMOTO, Chiyoji ABE, J. Yuzuru HOMMA, Yasuhiko KOJIMA

Journal:

Année:

1979

Langue:

english

Fichier:

PDF, 612 KB

english, 1979

13

Biological Activity of Chemically Synthesized Analogues of Lipid A : Demonstration of Adjuvant Effect in Hapten-Sensitized Liposomal System

Tatsuji YASUDA, Shiro KANEGASAKI, Toru TSUMITA, Takushi TADAKUMA, J. Yuzuru HOMMA, Masaru INAGE, Shoichi KUSUMOTO, Tetsuo SHlBA

Journal:

Année:

1982

Langue:

english

Fichier:

PDF, 322 KB

english, 1982

14

Interferon-inducing, pyrogenic and proclotting enzyme of horseshoe crab activation activities of chemically synthesized lipid A analogues

Motohiro MATSUURA, Yasuhiko KOJIMA, J. Yuzuru HOMMA, Yoshiyuki KUBOTA, Nobuyuki SHIBUKAWA, Masatoshi SHIBATA, Masaru INAGE, Shoichi KUSUMOTO, Tetsuo SHIBA

Journal:

Année:

1983

Langue:

english

Fichier:

PDF, 405 KB

english, 1983

15

Further study of biological activities of chemically synthesized analogues of lipid A in artificial membrane vesicles

Tatsuji YASUDA, Shiro KANEGASAKI, Toru TSUMITA, Takushi TADAKUMA, Nobunao IKEWAKI, J. Yuzuru HOMMA, Masaru INAGE, Shoichi KUSUMOTO, Tetsuo SHIBA

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 462 KB

english, 1984

16

Biological activities of analogues of lipid A based chemically on the revised structural model : Comparison of mediator-inducing, immunomodulating and endotoxic activities

Shiro KANEGASAKI, Yasuhiko KOJIMA, Motohiro MATSUURA, J. Yuzuru HOMMA, Akihiro YAMAMOTO, Yoshio KUMAZAWA, Ken-ichi TANAMOTO, Tatsuji YASUDA, Toru TSUMITA, Masahiro IMOTO, Hiroyuki YOSHIMURA, Michiharu

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 583 KB

english, 1984

17

The Identification of Vitamin E Homologues in Medicinal Plant Samples Using ESI(+)-LC-MS3

Inoue, Tomoko, Tatemori, Satoko, Muranaka, Natsumi, Hirahara, Yoshichika, Homma, Seiichi, Nakane, Takahisa, Takano, Akihito, Nomi, Yuri, Otsuka, Yuzuru

Journal:

Journal of Agricultural and Food Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 657 KB

english, 2012

18

Differences of chemical structures of Pseudomonas aeruginosa lipopolysaccharide essential for adjuvanticity and antitumor and interferon-inducing activities

Yangja Cho, Ken-ichi Tanamoto, Yanghyo Oh, J.Yuzuru Homma

Journal:

Année:

1979

Langue:

english

Fichier:

PDF, 274 KB

english, 1979

19

Proteolytic cleavage of exotoxin a form Pseudomonas aeruginosa: Formation of an ADP-ribosyltransferase active fragment by the action of Pseudomonas elastase

Yutaka Sanai, Kazuyuki Morihara, Hiroshige Tsuzuki, J.Yuzuru Homma, Iwao Kato

Journal:

Année:

1980

Langue:

english

Fichier:

PDF, 348 KB

english, 1980

20

Biological activities of chemically synthesized analogues of the nonreducing sugar moiety of lipid A

Motohiro Matsuura, Yasuhiko Kojima, J. Yuzuru Homma, Yoshiyuki Kubota, Akihiro Yamamoto, Makoto Kiso, Akira Hasegawa

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 354 KB

english, 1984

21

Effect of chemical modification at C1 of the glucosamine backbone of lipid A-subunit analog GLA-27 on manifestation of immunopharmacological activity

Yoshio Kumazawa, Hiroaki Takimoto, Akihiro Yamamoto, J.Yuzuru Homma, Yuji Ogawa, Makoto Kiso, Akira Hasegawa

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 314 KB

english, 1988

22

Nafamostat Preserves Neutrophil Deformability and Reduces Microaggregate Formation During Simulated Extracorporeal Circulation

Yuji Hiramatsu, Satoshi Homma, Yukio Sato, Shoko Sato, Kanji Matsuzaki, Osamu Shigeta, Yuzuru Sakakibara

Journal:

The Annals of Thoracic Surgery

Année:

2005

Langue:

english

Fichier:

PDF, 156 KB

english, 2005

23

Sivelestat Reduces Inflammatory Mediators and Preserves Neutrophil Deformability During Simulated Extracorporeal Circulation

Kanji Matsuzaki, Yuji Hiramatsu, Satoshi Homma, Shoko Sato, Osamu Shigeta, Yuzuru Sakakibara

Journal:

The Annals of Thoracic Surgery

Année:

2005

Langue:

english

Fichier:

PDF, 122 KB

english, 2005

24

Activated neutrophils and platelet microaggregates impede blood filterability through microchannels during simulated extracorporeal circulation

Yukihiro Yoshimura, Yuji Hiramatsu, Yukio Sato, Satoshi Homma, Yoshiharu Enomoto, Yuji Kikuchi, Yuzuru Sakakibara

Journal:

The Annals of Thoracic Surgery

Année:

2003

Langue:

english

Fichier:

PDF, 284 KB

english, 2003

25

ONO-6818, a novel, potent neutrophil elastase inhibitor, reduces inflammatory mediators during simulated extracorporeal circulation

Yukihiro Yoshimura, Yuji Hiramatsu, Yukio Sato, Satoshi Homma, Yoshiharu Enomoto, Tomoaki Jikuya, Yuzuru Sakakibara

Journal:

The Annals of Thoracic Surgery

Année:

2003

Langue:

english

Fichier:

PDF, 120 KB

english, 2003

26

Mucosal blood flow during various intravenous and inhalational anesthetics in the rabbit

Tatsuya Ichinohe, Yoshikazu Homma, Yuzuru Kaneko

Journal:

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Année:

1998

Langue:

english

Fichier:

PDF, 390 KB

english, 1998

27

Enhancement of nonspecific resistance to viral infection by chemically synthesized lipid A-subunit analogs with different backbone structures and acyl groups

Satoru Ikeda, Yoshio Kumazawa, Chiaki Nishimura, Mitsunobu Nakatsuka, J.Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

Antiviral Research

Année:

1988

Langue:

english

Fichier:

PDF, 575 KB

english, 1988

28

Antiviral and immunomodulating activities of chemically synthesized lipid A-subunit analogues GLA-27 and GLA-60

Satoru Ikeda, Chiaki Nishimura, Mitsunobu Nakatsuka, J. Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

Antiviral Research

Année:

1988

Langue:

english

Fichier:

PDF, 501 KB

english, 1988

29

Antiherpes activity of chemically synthesized lipid A-subunit analogue GLA-60 in immunosuppressed mice

Satoru Ikeda, Takanari Tominaga, Chiaki Nishimura, J.Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

Antiviral Research

Année:

1989

Langue:

english

Fichier:

PDF, 402 KB

english, 1989

30

Effect of acyl substituents of synthetic lipid A-subunit analogues on their immunomodulating antiviral activity

Satoru Ikeda, Chiaki Nishimura, Motohiro Matsuura, J.Yuzuru Homma, Makoto Kiso, Akira Hasegawa

Journal:

Antiviral Research

Année:

1990

Langue:

english

Fichier:

PDF, 338 KB

english, 1990

31

Characterisation of Maillard reaction products derived from LEKFD – A pentapeptide found in β-lactoglobulin sequence, glycated with glucose – By tandem mass spectrometry, molecular orbital calculations and gel filtration chromatography coupled with continuous photodiode array

Yamaguchi, Keiko, Homma, Takeshi, Nomi, Yuri, Otsuka, Yuzuru

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2014

32

Effects of Salt Concentration on the Reaction Rate of Glc with Amino Acids, Peptides, and Proteins

YAMAGUCHI, Keiko, NOUMI, Yuri, NAKAJIMA, Katsumi, NAGATSUKA, Chiharu, AIZAWA, Haruko, NAKAWAKI, Rie, MIZUDE, Eri, OTSUKA, Yuzuru, HOMMA, Takeshi, CHUYEN, Nguyen Van

Journal:

Bioscience Biotechnology and Biochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 199 KB

english, 2009

33

Derivatives of Dictyostelium differentiation-inducing factors inhibit lysophosphatidic acid–stimulated migration of murine osteosarcoma LM8 cells

Kubohara, Yuzuru, Komachi, Mayumi, Homma, Yoshimi, Kikuchi, Haruhisa, Oshima, Yoshiteru

Journal:

Biochemical and Biophysical Research Communications

Année:

2015

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2015

34

THE CHROMATOGRAPHIC PURIFICATION OF BACTERIOPHAGE AND ENDOTOXIN OF PSEUDOMONAS AERUGINOSA

Homma, J. Yuzuru, Hamamura, Norikatsu, Ashizawa, Yoshio

Journal:

Japanese Journal of Microbiology

Année:

1961

Langue:

english

Fichier:

PDF, 2.03 MB

english, 1961

35

Supplement 5. Symposium on Pseudomonas aeruginosa Infections || Effectiveness of Immunization with Multicomponent Vaccines in Protection against Hemorrhagic Pneumonia Due to Pseudomonas aeruginosa Infection in Mink

J. Yuzuru Homma, Chiyoji Abe, Ryo Yanagawa and Hiroshi Noda

Journal:

Reviews of Infectious Diseases

Année:

1983

Langue:

english

Fichier:

PDF, 459 KB

english, 1983

36

Simultaneous Quantitation of Advanced Glycation End Products in Soy Sauce and Beer by Liquid Chromatography-Tandem Mass Spectrometry without Ion-Pair Reagents and Derivatization

Nomi, Yuri, Annaka, Hironori, Sato, Shinji, Ueta, Etsuko, Ohkura, Tsuyoshi, Yamamoto, Kazuhiro, Homma, Seiichi, Suzuki, Emiko, Otsuka, Yuzuru

Journal:

Journal of Agricultural and Food Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 821 KB

english, 2016

37

Studies of Pseudomonas Aeruginosa Mucosus Strains Persistently Isolated from a Patient of Chronic Bronchitis and a Trial of Autogenous Vaccines as a Treatment

OKANO, Hiroshi, HOMMA, Yuzuru, SHIONOYA, Hiroshi

Journal:

Kansenshogaku zasshi

Année:

1970

Fichier:

PDF, 4.25 MB

1970

38

Prevelance of Antibodies to OEP, Exotoxin A, and Exoenzymes of Pseudomonas aeruginosa in Man

SHINOZAKI, Tatsuhiko, FUJII, Ryochi, SANAI, Yutaka, HOMMA, J. Yuzuru

Journal:

Kansenshogaku zasshi

Année:

1981

Fichier:

PDF, 1.09 MB

1981

39

Anti-Leukocidin Antibody in Sera of Diffuse Panbronchiolitis Patients

KAZUYAMA, Yukumasa, SIBATA, Masatoshi, YAMAMOTO, Mitsuru, KUBOTA, Yoshiyuki, MATSUURA, Motohiro, HOMMA, Yuzuru, HIRAYAMA, Toshiya, KATO, Iwao

Journal:

Kansenshogaku zasshi

Année:

1985

Fichier:

PDF, 399 KB

1985

40

Production of Leukocidin of Pseudomonas aeruginosa Strains Isolated from Patients and Environmental Specimens

SIBATA, Masatoshi, KAZUYAMA, Yukumasa, YAMAMOTO, Mitsuru, KUBOTA, Yoshiyuki, MATSUURA, Motohiro, HOMMA, Yuzuru, HIRAYAMA, Toshiya, KATO, Iwao

Journal:

Kansenshogaku zasshi

Année:

1985

Fichier:

PDF, 4.78 MB

1985

41

Antibody Titers in the Serum of Patients Vaccinated with the Multicomponent Vaccine Consisting of Toxoids of Protease, Elastase and a Common Protective Antigen (OEP)

YAMAMOTO, Mitsuru, KUBOTA, Yoshiyuki, MATSUURA, Motohiro, HOMMA, J. Yuzuru

Journal:

Kansenshogaku zasshi

Année:

1986

Fichier:

PDF, 791 KB

1986

42

Synergistic effects of a macrolide and a cell wall-affecting antibiotic on Pseudomonas aeruginosa in vitro and in vivo. 3. Incorporation of (14C)midecamycin acetate (MOM) into P. aeruginosa pretreated with cell wall-affecting antibiotics.

KASAI, TAKAO, TOMITA, TOSHIO, KANEGASAKI, SHIRO, HOMMA, J. YUZURU

Journal:

The Journal of Antibiotics

Année:

1982

Langue:

english

Fichier:

PDF, 3.34 MB

english, 1982

43

Synergistic effects of a macrolide and a cell wall-affecting antibiotic on Pseudomonas aeruginosa in vitro and in vivo. 2. Combined effects of a macrolide with a Fosfomycin and an aminoglycoside antibiotic.

KASAI, TAKAO, HOMMA, J. YUZURU

Journal:

The Journal of Antibiotics

Année:

1982

Langue:

english

Fichier:

PDF, 3.96 MB

english, 1982

44

Therapeutic effect of intracorneal injection of immunoglobulins on corneal ulcers in horses experimentally infected with Pseudomonas aeruginosa.

UEDA, Yahiro, SANAI, Yutaka, HOMMA, J.Yuzuru

Journal:

The Japanese Journal of Veterinary Science

Année:

1982

Fichier:

PDF, 1016 KB

1982

45

Synergistic effects of a macrolide and a cell wall-affecting antibiotic on Pseudomonas aeruginosa in vitro and in vivo. 1. Combined effects of a macrolide and a peptide antibiotic.

KASAI, TAKAO, HOMMA, YUZURU

Journal:

The Journal of Antibiotics

Année:

1982

Langue:

english

Fichier:

PDF, 3.01 MB

english, 1982

46

Effects of Immunization of Horses with Common Antigen (OEP), Protease Toxoid, and Elastase Toxoid on Corneal Ulceration Due to Pseudomonas aeruginosa Infection

UEDA, Yahiro, HOMMA, J.Yuzuru, ABE, Chiyoji

Journal:

The Japanese Journal of Veterinary Science

Année:

1982

Fichier:

PDF, 1.60 MB

1982

47

Determination of Furosine and Fluorescence as Markers of the Maillard Reaction for the Evaluation of Meat Products during Actual Cooking Conditions

YAMAGUCHI, Keiko, NOMI, Yuri, HOMMA, Takeshi, KASAI, Midori, OTSUKA, Yuzuru

Journal:

Food Science and Technology Research

Année:

2012

Langue:

english

Fichier:

PDF, 710 KB

english, 2012

48

Enhanced Chemiluminescence Response of Phagocyting Monocytes from Sarcoidosis Patients

Kanegasaki, Shiro, Homma, Yuzuru, Homma, Hiomi, Washizaki, Makoto

Journal:

International Archives of Allergy and Immunology

Année:

1981

Langue:

english

Fichier:

PDF, 869 KB

english, 1981

49

Structural Requirements of Lipid A Responsible for the Functions: A Study with Chemically Synthesized Lipid A and Its Analogues1

HOMMA, J. Yuzuru, MATSUURA, Motohiro, KANEGASAKI, Shiro, KAWAKUBO, Yasuaki, KOJIMA, Yasuhiko, SHIBUKAWA, Nobuyuki, KUMAZAWA, Yoshio, YAMAMOTO, Akihiro, TANAMOTO, Ken-ichi, YASUDA, Tatsuji, IMOTO, Masa

Journal:

Journal of Biochemistry

Année:

1985

Langue:

english

Fichier:

PDF, 4.24 MB

english, 1985

50

Structure-Activity Relationship of Lipid A: Comparison of Biological Activities of Natural and Synthetic Lipid A's with Different Fatty Acid Compositions1

KANEGASAKI, Shiro, TANAMOTO, Ken-ichi, YASUDA, Tatsuji, HOMMA, J. Yuzuru, MATSUURA, Motohiro, NAKATSUKA, Mitsunobu, KUMAZAWA, Yoshio, YAMAMOTO, Akihiro, SHIBA, Tetsuo, KUSUMOTO, Shoichi, IMOTO, Masahi

Journal:

Journal of Biochemistry

Année:

1986

Langue:

english

Fichier:

PDF, 451 KB

english, 1986